Exploring the role of US payers in evidence generation: a call to action? 

A recent JAMA article by Robert Califf and co-authors underscores the crucial role that private payers in the US can play in enhancing evidence generation.  As regulatory agencies, like the FDA, are placing greater emphasis on post-market evidence generation, a new article published in JAMA calls on private payers in the US to actively contribute to this initiative. In the piece, led by FDA Commissioner Robert Califf, the authors draw on the experience of public payers, such as the Centers for Medicare and Medicaid Services (CMS), offering insights to, “ensure that the opportunities to participate in clinical research are extended...